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The CNLM supports work in three types of nutrition and cognition research: basic research, optimization of assessment and testing tools, and translational or clinical research. Project teams include a principal investigator whose primary appointment is at the University of Illinois at Urbana-Champaign. Teams are interdisciplinary and include a diverse group of researchers that represent 15 Illinois departments or units, 6 Illinois colleges. Larger projects include collaborators from at least 12 national and international research sites.

Basic research

  • A Nutritional Intervention to Enhance Brain and Cognitive Development in Small-for-Gestational-Age Piglets
  • Brain and Cognitive Development in Small-for-Gestational Age Piglets
  • Cognitive Nutrients and the Brain: Production of Isotopically Labeled Nutrients and Development of Animal Models
  • Development of a Small-for-Gestational-Age Piglet Model
  • Diet-Modified Brain Chemistry and Plasticity: Nutrition as a Case Study
  • The Effects of a Bioactive Nutrient on Cognitive Functioning in an Animal Model of Normal Aging
  • Enhancing Learning and Memory in the Aged: Interactions Between Dietary Supplementation and Exercise
  • Impact of Fiber on the Gut Microbiome and Cognition in Mice
  • Impact of Infant Formula on Brain and Eye Development
  • Impact of Nutrients on Neonatal Brain Development and Function  
  • Impact of Select Nutrients on Eye and Brain Health
  • Molecular Basis of Cognitive Impairment in “ChemoBrain” and Nutritional Intervention
  • Neural Mechanisms of Nutrient-Induced Cognitive Enhancement
  • Nutritional Enhancement of Cognition Through Stem Cells
  • Protection of Biomolecules by Dietary Nutrients and Exacerbation of Oxidative Stress by Impaired Nutrient Supply

Optimization of assessment and testing tools

  • Developing Advanced MRI Methods for Detecting the Impact of Nutrients on Infant Brain Development
  • Development of a Methodology for Investigating the Effects of Nutrition on the Maturation of Brain Networks Associated with Memory and Language in Infants
  • Diet-Modified Neuron Physiology Assessments
  • Enhanced Chemical Characterization Efforts for Selected CNLM Projects
  • Enhanced Morphological Measurement Capabilities for Selected CNLM Projects
  • Mouse Cognition Core Facility
  • Mouse Cognition and Hippocampal Neurogenesis Core Facility
  • Optimizing Assessment Tools for Determining Nutritional Enhancement of Learning and Memory
  • Probing the Effect of Brain Metabolism on Cognitive Function
  • Understanding the Effects of Nutritional Supplements on Function and Development of Human Neuronal Cells
  • Visualizing Diet-Modified Brain Chemistry with Multifaceted Chemical Imaging

Translational or clinical research

  • A Short-Term Longitudinal Study of Pre-Term Infant Neurodevelopment
  • Cognitive and Brain Development in Premature Infants: Validation of a New Approach
  • Controlled Trials in ‘At Risk’ Humans to Establish the Cognitive Benefits of a Nutrient Mixture and Underlying Mechanisms of Action
  • The Effects of Fortified Nutritional Supplementation on Cognition, Memory, & Achievement
  • Investigating the Effects of Nutrition on the Maturation of Brain Networks Associated with Memory in Infants
  • Longitudinally Dynamic Biomarkers of Healthy Brain Aging in the Illinois Elderly Adult Cohort
  • Nutritional Enhancement of Cognitive and Physical Performance: A Randomized Controlled Trial
  • Nutritional Intake, Cognitive Function and Measures of Brain Aging
  • Retrospectively Studying the Effects of Early Life Nutrient Intake on Cognitive Function and Brain Health in Preadolescent Children
  • The Role of Neurotransmitters in Obesity, Food-Choice, and Memory-Related Processes
  • Synergistic Effects of Exercise and Nutrition on Cognition & Brain Health of Older Adults: A Randomized Controlled Trial